Tag results:
neurons
Neural Cell News
Tsp-1 Is Involved in DNA Stability through TGF-β1 Activation Domain in Cone Photoreceptor 661 W Cells
[Cell and Tissue Research] Data showed that thrombospondin-1 (Tsp-1) downregulation aggravated UV irradiation-induced DNA damage in 661 W cells and cone photoreceptor cells.
Neural Cell News
Ferroptosis in Parkinson’s Disease: Glia–Neuron Crosstalk
[Trends in Molecular Medicine] Investigators review the association between iron deposition, glial activation, and neuronal death, and discuss whether and how ferroptosis affects α-synuclein aggregation and dopaminergic neuron loss.
Extracellular Matrix News
NSC-Derived Extracellular Matrix-Modified GelMA Hydrogel Fibrous Scaffolds for Spinal Cord Injury Repair
[NPG Asia Materials] Researchers developed gethacrylate gelatin (GelMA)/ECM hydrogel fibrous scaffolds that could recruit and enhance the differentiation of neural stem cells by electrospinning and decellularization techniques.
Extracellular Matrix News
Pharmacological Perturbation of Mechanical Contractility Enables Robust Transdifferentiation of Human Fibroblasts into Neurons
[Advanced Science] The authors reported a robust method to convert fibroblasts to neurons through targeting the cytoskeleton followed by exposure to lineage-specification surroundings.
Extracellular Matrix News
Biohaven Licenses Taldefgrobep Alfa, a Phase III-Ready Anti-Myostatin Adnectin for Spinal Muscular Atrophy (SMA), from Bristol Myers Squibb
[Biohaven Pharmaceutical Holding Company Ltd.] Biohaven Pharmaceutical Holding Company Ltd. announced that it entered into a license agreement with Bristol Myers Squibb for the development and commercialization rights to taldefgrobep alfa, a novel, Phase III-ready anti-myostatin adnectin.
ESC & iPSC News
Metabolites of Soil Microorganisms Modulate Amyloid β Production in Alzheimer’s Neurons
[Scientific Reports] Researchers conducted a library screening to quantify amyloid β and neuronal toxicity by using cortical neurons from hiPSCs of AD patients after adding secondary metabolites.