neutrophils

[Cell Death & Disease] The authors investigated the impact of apoptotic colorectal cancer cells on neutrophils and its consequence on other immune cells of the tumor microenvironment.

[FASEB Journal] Scientists evaluated the effects of the specialized pro-resolving mediators lipids, lipoxin A4 and lipoxin B4, on neutrophils isolated from patients with atherosclerosis compared with healthy controls.

[Scientific Reports] Leukocyte, platelet, neutrophil, and lymphocyte counts were assessed. Scientists analyzed the association of neutrophil-derived factors with clinical severity scoring systems.

[Gut] Scientists investigated the cellular source for secreted anterior gradient-2 (AGR2) in the tumor microenvironment and underlying mechanisms mediating secreted AGR2’s effects.

[Aging] Investigators indicated that TEAD2/4 were significantly upregulated in HCC compared with normal tissues. Downregulation of TEAD2 promoted the death of HCC cells through inducing ferroptosis by iron accumulation and subsequent oxidative damage.

[Cancer Discovery] Researchers unveiled the ectonucleotide pyrophosphatase /phosphodiesterase 1 (ENPP1)/HP axis as an unanticipated mechanism exploited by tumor cells linking inflammation to immune remodeling favoring local relapse.