organoids

[Ecotoxicology and Environmental Safety] Researchers described a novel computational method for characterizing toxicity, associated biological perturbations and disease outcome, called the Chemo-Phenotypic Based Toxicity Measurement. The method was validated in the in vitro, in vivo and organoid models.

[Ecotoxicology and Environmental Safety] Researchers described a novel computational method for characterizing toxicity, associated biological perturbations and disease outcome, called the Chemo-Phenotypic Based Toxicity Measurement. The method was validated in the in vitro, in vivo and organoid models.

[Communications Biology] Researchers developed a tool, named BrewerIX, that provided comprehensive information about the allelic expression of a large, manually-curated set of imprinted and X-linked genes.

[Science Advances] In this proof-of-concept study, the authors successfully established organoids from seven chordoma tumor samples obtained from five patients presenting with tumors in different sites and stages of disease.

[Cancer Letters] The authors investigated the role of the tumor stem cell marker DCLK1 in epithelial growth factor receptor-tyrosine kinase inhibitor resistance of lung adenocarcinoma.

[Science Advances] Scientists demonstrated that in human neural stem cells, lysosomes are asymmetrically inherited during mitosis.