organoids

[iScience] Researchers developed an esophageal minimum essential organoid culture medium for culturing murine esophageal organoid and establishing an early esophageal squamous cell carcinoma model.

[iScience] Scientists developed a highly standardized, reproducible and fast murine brain organoid model starting from embryonic neural stem cells.

[American Journal of Physiology-Gastrointestinal and Liver Physiology] Scientists showed that IL22 treatment induced the phosphorylation of STAT3, inhibited colonic organoid growth, and promoted colonic cell proliferation in vivo.

[Nature Protocols] Researchers provided a detailed protocol describing how to form heart-forming organoids within 14 days, that could be used on many different human PSC lines and be combined with manipulation technologies such as gene targeting and drug testing.

[Nature Communications] Generation of kidney organoids from Tuberous Sclerosis Complex patient-derived-human iPSCs allowed researchers to recapitulate a rare kidney tumor called angiomyolipoma.

[Cancer Research] Investigators showed that membranous HER3 protein was commonly highly expressed in lethal prostate cancer, associating with reduced time to castration resistance and survival.