pancreatic cancer cells

[Acta Histochemica] Scientists evaluated the expression of survivin by real-time PCR, and the expression levels of proteins involved in apoptosis, autophagy, and PI3K/Akt/mTOR signaling were detected by western blotting.

[Communications Biology] In vitro results showed that low-density lipoprotein receptor (LDLR)-targeting conjugate entered into PDAC cells through LDLR mediated-endocytosis before trafficking to the late endosome/lysosome pathway, emulating the natural ligand low-density lipoprotein.

[Journal of Pathology Clinical Research] Scientists unearthed RBM3-regulated genes and proteins in pancreatic cancer cells in vitro, and to examine their expression and prognostic significance in human tumors.

[Cancer Immunology Immunotherapy] Researchers studied the interaction between pancreatic ductal adenocarcinoma (PDAC) cells and pancreatic stellate cells (PSCs) in vitro and verified their finding with the survival data of patients with PDAC from the website of The Human Protein Atlas.

[Analytical Chemistry] An inductively coupled plasma mass spectrometry (ICP-MS) and photothermal dual-readout platform was proposed for the ultrasensitive and point-of-care analysis of pancreatic cancer exosomes.

[Biochimica Et Biophysica Acta-Molecular Basis of Disease] Scientists demonstrated that tripartite motif (TRIM) expression was elevated in pancreatic ductal adenocarcinomas tissues, and this elevated expression was associated with a poor prognosis.