pancreatic cancer cells

[Cells] evaluated the toxic effect of glyceraldehyde-derived intracellular AGEs on normal and malignant pancreatic ductal cells by assessing the cell viability, toxicity, and oxidative stress, followed by proteomic analysis.

[Cancer Research] Scientists generated pancreatic cancer cells resistant to Mek1/2 inhibition, which were also resistant to KRAS and Erk1/2 inhibitors.

[Journal of Gene Medicine] Researchers investigated whether miR‐26b regulated CDK14 expression to affect the phenotype of pancreatic cancer cells.

[BMC Cancer] Researchers investigated whether kaempferol effectively suppressed pancreatic cancer through upregulation of reactive oxygen species (ROS), and explored the underlying molecular mechanism.

[Cell Death Discovery] Scientists demonstrated that NR5A2 acted as a negative prognostic biomarker in PDAC. NR5A2 silencing inhibited the proliferation and migration abilities of pancreatic cancer cells in vitro and in vivo.

[Molecular Oncology] Scientists confirmed that mind bomb 1 (MIB1) expression was elevated in pancreatic cancer tissues and that high levels of MIB associate with unfavorable prognosis. Overexpression of MIB1 enhanced proliferation and invasion of pancreatic cancer cells both in vitro and in vivo.