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pancreatic cells

Modulation of Pancreatic Cancer Cell Sensitivity to FOLFIRINOX through microRNA-Mediated Regulation of DNA Damage

[Nature Communications] Scientists found that 41 and 84 microRNA inhibitors enhanced the sensitivity of Capan1 and MiaPaCa2 pancreatic ductal adenocarcinoma cells respectively.

MCT4 as a Potential Therapeutic Target to Augment Gemcitabine Chemosensitivity in Resected Pancreatic Cancer

[Cellular Oncology] Investigators identified the prognostic significance and therapeutic options of metabolic subtypes of resectable pancreatic cancer.

HIG1 Domain Family Member 1A Disrupts Proliferation, Migration and Invasion of Colon Adenocarcinoma Cells

[Bioengineered] Higd-1a promotes the proliferation of pancreatic cancer cells and the growth of pancreatic cancer; however, no similar observations have been reported for colorectal cancer (CRC). This study, researchers verified the role of Higd-1a in colorectal cancer.

MicroRNA-190b Expression Predicts a Good Prognosis and Attenuates the Malignant Progression of Pancreatic Cancer by Targeting MEF2C and TCF4

[Oncology Reports] Scientists examined the expression of miR‑190b in pancreatic cancer cell lines and tissues and evaluated its effects on cancer progression.

Localized Drug Delivery Graphene Bioscaffolds for Cotransplantation of Islets and Mesenchymal Stem Cells

[Science Advances] Scientists developed, characterized, and tested an implantable graphene bioscaffold which elutes dexamethasone that could accommodate islets and adipose tissue–derived MSCs.

Apoptosis-Associated Speck-Like Protein Containing a CARD Regulates the Growth of Pancreatic Ductal Adenocarcinoma

[Scientific Reports] Scientists clarified the role and mechanisms of action of apoptosis-associated speck-like protein containing a caspase recruitment domain in pancreatic ductal adenocarcinoma using clinical evidence and in vitro data.

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