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pancreatic cells

Pancreatic Extracellular Matrix/Alginate Hydrogels Provide a Supportive Microenvironment for Insulin-Producing Cells

[ACS Biomaterials Science & Engineering] Hydrogel prepared with alginate and the pancreatic extracellular matrix was assessed for the beneficial outcomes on encapsulated insulin-producing cells.

An Exosome-Mimicking Membrane Hybrid Nanoplatform for Targeted Treatment toward Kras-Mutant Pancreatic Carcinoma

[Biomaterials Science] Scientists constructed a hybrid nanoplatform by fusing Celastrol-Loaded PEGylated lipids with the DC2.4 cell membrane to achieve targeted treatment of Kras-mutant pancreatic cancer.

The Discovery of Indolone GW5074 during a Comprehensive Search for Non-Polyamine-Based Polyamine Transport Inhibitors

[International Journal of Biochemistry & Cell Biology] Researchers presented the first comprehensive search for potential non-polyamine based polyamine transport inhibitors that work in human pancreatic cancer cells in vitro.

SARS-CoV-2 Infection of the Pancreas Promotes Thrombo-Fibrosis and Is Associated with New-Onset Diabetes

[JCI Insight] Scientists reported expression of angiotensin-converting enzyme 2 in pancreatic islet, ductal, and endothelial cells in non-human primates and humans.

Auris Medical to Develop KRAS-Targeting RNA Treatment for Colorectal Cancer as First Therapeutic Indication for OligoPhoreâ„¢ Technology

[Auris Medical Holding Ltd.] Auris Medical Holding Ltd. announced the selection of mutant KRAS-driven colorectal cancer as the first therapeutic indication for its OligoPhoreâ„¢ oligonucleotide delivery platform, based on outcomes from studies with OligoPhoreâ„¢ enabled KRAS silencing, and a well-defined regulatory and development pathway.

Fetuin-A Excess Expression Amplifies Lipid Induced Apoptosis and β-Cell Damage

[Journal of Cellular Physiology] Scientists validated the effect of fetuin-A release and lipid induced apoptosis in mouse insulinoma cell line MIN6.

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