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prostate cancer

Insights into Homeobox B9: A Propeller for Metastasis in Dormant Prostate Cancer Progenitor Cells

[British Journal of Cancer] Investigators established prostate cancer (PCa) models via the orthotopic and subcutaneous implantation of different human PCa cancer cell lines, and compared the metastatic efficacy, after which process function analysis of target genes was pinpointed.

Sonlicromanol’s Active Metabolite KH176m Normalizes Prostate Cancer Stem Cell mPGES-1 Overexpression and Inhibits Cancer Spheroid Growth

[PLOS One] Investigators investigated whether KH176m, a recently discovered selective mPGES-1 inhibitor, could affect prostate cancer cells-derived spheroid growth.

Overexpression of Claspin Promotes Docetaxel Resistance and Is Associated with Prostate-Specific Antigen Recurrence in Prostate Cancer

[Cancer Medicine] Scientists aimed to elucidate the role of claspin and its relationship with docetaxel resistance in prostate cancer.

Metabolic Reprogramming in Prostate Cancer

[British Journal of Cancer] Scientists focus on alterations in the metabolism of prostate cancer, including genetic signatures and molecular pathways associated with metabolic reprogramming.

Stromal Cell Interplay in Prostate Development, Physiology, and Pathological Conditions

[Prostate] The authors provide an update on the different types of prostate stromal cells, their interrelationships and implications for prostate development, physiology and pathological conditions.

Lava Therapeutics Announces Treatment of First Patient in Phase I/IIa Clinical Trial of LAVA-051 for Multiple Hematological Malignancies

[LAVA Therapeutics, N.V.] LAVA Therapeutics N.V. announced dosing of the first patient in the company’s Phase I/IIa clinical trial of LAVA-051 in patients with relapsed and/or refractory chronic lymphocytic leukemia, multiple myeloma and acute myeloid leukemia.

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