pulmonary cells

[Scientific Reports] Physiochemical properties, encapsulation efficiency, loading content and in vitro release kinetics of DOX were assessed in MUC1 aptamer-functionalized PLA-PEG nanocarriers targeting lung cancer cells.

[Thorax] Given that COPD often shares structural features with Birt-Hogg-Dubé syndrome, scientists investigated the link between COPD, cigarette smoke exposure and folliculin gene expression.

[Scientific Reports] The authors explored the anti-inflammatory effects and underlying molecular mechanism of povidone-iodine (PVP-I) on lipopolysaccharide-stimulated airway epithelial cells and investigated whether nasal instillation of PVP-I could suppress mucosal inflammation in non-eosinophilic chronic rhinosinusitis mice.

[Bioengineered] Investigators revealed the role of CALR in lung cancer cells, indicating that highly expressed CALR proliferation at least by activation of NF-ĸB signaling pathway.

[Biochemistry and Cell Biology] The effects of small proline rich protein 1A (SPRR1A) on lung cancer cells were tested through cellular experiments and the result demonstrated that knockdown of SPRR1A could suppress proliferation and invasion capacities of tumor cells, while overexpressing SPRR1A exerted opposite effects.

[npj Precision Oncology] STAT3 inhibition effectively suppressed the adaptive survival of anaplastic lymphoma kinase (ALK)-rearranged lung cancer cells by enhancing ALK inhibition-induced apoptosis.