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SARS-CoV-2

Mesenchymal Stromal Cells for Enhancing Hematopoietic Engraftment and Treatment of Graft-Versus-Host Disease, Hemorrhages and Acute Respiratory Distress Syndrome

[Frontiers in Immunology] The authors summarize current evidence from in vitro studies, animal models, and their clinical experience, to support stromal cell therapy in multiple clinical indications.

An Extended Conformation of SARS-CoV-2 Main Protease Reveals Allosteric Targets

[Proceedings of the National Academy of Sciences of the United States of America] The authors obtained the extended conformation of the native monomer of SARS-CoV-2 main protease by trapping it with nanobodies, and found that the catalytic domain and the helix domain dissociated, revealing allosteric targets.

COVID-19: Autoimmunity, Multisystemic Inflammation and Autoimmune Rheumatic Patients

[Molecular Medicine] Based on evidence from the literature, as well as international scientific recommendations, the authors review the relationships between COVID-19, autoimmunity and patients with autoimmune rheumatic and musculoskeletal disease.

Human Placenta-Derived Amniotic Epithelial Cells as a New Therapeutic Hope for COVID-19-Associated Acute Respiratory Distress Syndrome (ARDS) and Systemic Inflammation

[Stem Cell Research & Therapy] Investigators focus on the proposed early and late therapeutic mechanisms of human amniotic epithelial cells and their exosomes to the injured organs.

Allelic Imbalance of HLA-B Expression in Human Lung Cells Infected with Coronavirus and Other Respiratory Viruses

[European Journal of Human Genetics] Investigators discovered an increased allelic expression pattern accompanied with overexpression of human leucocyte antigen (HLA)-B gene in SARS-CoV-2-infected human lung epithelial cells.

Optimization of VSV-ΔG-Spike Production Process with the Ambr15 System for a SARS-COV-2 Vaccine

[Biotechnology and Bioengineering] Investigators reported the optimization of the production of VSV-ΔG-spike vaccine in Vero cells using the Ambr15 system.

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