smooth muscle cells

[Journal of Cellular and Molecular Medicine] Using miRNA sequencing and real-time PCR, we found that fibroblast growth factor 21 (FGF21) treatment inhibited miR-130 elevation in hypoxia-induced PAH in vitro and in vivo.

[Journal of Molecular and Cellular Cardiology] Researchers established the ability of the polyphenol compound epigallocatechin gallate, a principal component of green tea, to facilitate the extracellular formation of elastin fibers in vascular smooth muscle cells derived from human induced pluripotent stem cells.

[Theranostics] By use of single-cell RNA-sequencing and multi-color staining, scientists delineated the cellular composition and spatial characterization of human aorta with or without aortic dissection.

[Peptides] Researchers investigated the mechanism of high glucose-induced endothelin type B (ETB) receptors in vascular smooth muscle cell.

[Pharmacological Research] Researchers found that the level of lactate dehydrogenase A (LDHA) was significantly elevated in aortic dissection patients and the mouse model established by BAPN combined with Ang II.

[Aging] Scientists explored the roles and underlying mechanism of exosomes derived from endothelial cells (ECs) in the crosstalk between ECs and vascular smooth muscle cells.