Tag results:
tuberculosis
Immunology of Infectious Disease News
Point-of-Care Diagnostic Tests for Tuberculosis Disease
[Science Translational Medicine] Scientists evaluate current diagnostic assays endorsed by the World Health Organization and identify the gaps between existing conventional tests and the ideal point-of-care test for tuberculosis disease.
Immunology of Infectious Disease News
Chemical–Genetic Interaction Mapping Links Carbon Metabolism and Cell Wall Structure to Tuberculosis Drug Efficacy
[Proceedings of the National Academy of Sciences of the United States of America] The authors utilized conditional Mycobacterium tuberculosis (Mtb) knockdown mutants of essential genes as an experimentally tractable surrogate for drug treatment and probed the relationship between Mtb carbon metabolism and chemical-genetic interactions
Immunology of Infectious Disease News
Mice Infected with Mycobacterium tuberculosis Are Resistant to Acute Disease Caused by Secondary Infection with SARS-CoV-2
[PLoS Pathogens] In both model systems, Mycobacterium tuberculosis (Mtb)-infected mice were resistant to the pathological consequences of secondary SARS-CoV-2 infection, and SARS-CoV-2 infection did not affect Mtb burdens.
Immunology of Infectious Disease News
Platelets Accumulate in Lung Lesions of Tuberculosis Patients and Inhibit T Cell Responses and Mycobacterium tuberculosis Replication in Macrophages
[European Journal of Immunology] In vitro activated platelets inhibited Bacillus Calmette-Guerin-induced T lymphocyte proliferation and IFN-γ production.
Immunology of Infectious Disease News
Surveying the Epigenetic Landscape of Tuberculosis in Alveolar Macrophages
[Infection and Immunity] Investigators compare the fundamental differences between alveolar macrophages and circulating monocyte-derived macrophages in the context of tuberculosis and summarize the recent advances in elucidating the epigenomes of these cells.
Immunology of Infectious Disease News
Surge of HIV, Tuberculosis and COVID Feared amid War in Ukraine
[NatureNews] Adding to the brutal, immediate effects of Russia’s invasion, the Ukrainian people are facing an onslaught of infectious diseases. Some threats — such as the spread of COVID-19 — are immediate, as people huddle in basements, subway stations and temporary shelters to protect themselves from bombardments.