Publication

[Hepatology Communications] TATA-box-binding protein expression was measured by PCR, western blot, and immunohistochemistry. RNA-sequencing was performed to identify downstream proteins.

[Environmental Toxicology] In HCC tissues, differentially expressed long noncoding RNAs (lncRNAs) were identified by bioinformatics. AC012360.1 level was validated and its role in HCC progression was investigated.

[iScience] The authors established patient-derived tumor organoids and performed a drug test in 277 samples from 242 colorectal cancer patients who received FOLFOX or XELOX chemotherapy.

[Molecular Cancer Therapeutics] To identify drugs that could enhance the efficacy of MEK inhibitors, researchers performed unbiased high-throughput screening using colorectal cancer spheroids.

[Scientific Reports] The cell proliferation capacity of HCT116 and SW480 cells was assessed using the CCK-8 and EdU assays. Cell apoptosis was tested through flow cytometry, and cell migration and invasion were examined using the transwell assay.

[American Journal Of Physiology-Gastrointestinal And Liver Physiology] Researchers described the common activation of the zinc finger transcription factor and Let-7 target PLAGL2 in colorectal cancer and found that it was a key driver of intestinal epithelial transformation.