Tag results:

Publication

Engineering Magnetotactic Bacteria MVs to Synergize Chemotherapy, Ferroptosis and Immunotherapy for Augmented Antitumor Therapy

[Nanoscale Horizons] Inspired by the development of synergistic therapeutic strategies, scientists proposed a novel nanovaccine-based platform to achieve chemotherapy, ferroptosis therapy, and immunotherapy simultaneously.

Lipid Nanoparticle mRNA Systems Containing High Levels of Sphingomyelin Engender Enhanced Protein Expression in Hepatic and Extra-Hepatic Tissues

[Molecular Therapy-Methods & Clinical Development] The authors investigated the properties of lipid nanoparticles-mRNA systems prepared with high levels of “helper” lipids such as distearoyl phosphatidylcholine or egg sphingomyelin.

Decellularized Periosteum Promotes Guided Bone Regeneration via Manipulation of Macrophage Polarization

[Biotechnology Journal] Researchers fabricated decellularized periosteum (DP) and investigate its immunomodulatory properties in guided bone regeneration. DP was successfully fabricated from periosteum from the mini-pig cranium.

Chimeric Antigen Receptor (CAR) T Cells for the Treatment of a Kidney Transplant Patient with Post-transplant Lymphoproliferative Disorder (PTLD)

[Human Vaccines & Immunotherapeutics] Investigators showed that even with the background of prolonged immunosuppression for solid organ transplant, it is possible to generate autologous CAR-T products capable of expansion and persistence in vivo, without evidence of excess T cell exhaustion.

TMEM11 Regulates Cardiomyocyte Proliferation and Cardiac Repair via METTL1-Mediated m7G Methylation of ATF5 mRNA

[Cell Death & Differentiation] Investigators detected that the mitochondrial transmembrane protein 11 inhibited cardiomyocyte proliferation and cardiac regeneration in vitro.

Understanding Spatiotemporal Mechanical Behavior, Viscoelasticity, and Functions of Stem Cell-Derived Cardiomyocytes

[Nanoscale] To probe the time-dependent viscoelastic behaviors of cardiomyocytes with cross-linked polymer networks, the authors measured stem cell-derived cardiomyocyte's deformation, adhesion, and contractility using atomic force microscopy nanoindentation, fluidic micropipette, and digital image correlation.

Popular