Publication

[Acta Pharmacologica Sinica] Investigators systematically explored the validity of sequential ALK inhibitors for a heavy-treated patient with EML4-ALK fusion via developing an in vitro and in vivo drug testing system based on patient-derived models.

[Nature Communications] Investigators developed a biomaterial system consisting of elastic porous poly(l-lactide-co-ε-caprolactone) microspheres mixed with ECM hydrogels as injectable composites with interleukin-4 and insulin-like growth factor-1 dual-release functionality.

[Scientific Reports] Scientists explored the phenotypes and subsets of macrophages following treatment with the active constituent of Collagenase Santyl® Ointment.

[Advanced Healthcare Materials] Researchers presented a novel 3D in vitro model mimicking intracranial myeloid sarcoma, employing a hydrogel scaffold derived from the brain-decellularized extracellular matrix in which suspended leukemia cells were embedded, simulating the formation of tumor masses in the brain parenchyma.

[Advanced Science] A stent-free anti-stenosis drug coating based on a peptide hydrogel was proposed. The hydrogel was formed by assembling a nitric oxide donor-peptide conjugate as a hydrogelator and encapsulating curcumin during the assembly process.

[Scientific Reports] Scientists investigated the effectiveness of Platelet Rich Plasma vs. Mineral Trioxide Aggregate as a direct pulp capping agent. 42 teeth from three mongrel dogs were divided into two equal groups.