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Brain-Decellularized ECM-Based 3D Myeloid Sarcoma Platform: Mimicking Adaptive Phenotypic Alterations in the Brain

[Advanced Healthcare Materials] Researchers presented a novel 3D in vitro model mimicking intracranial myeloid sarcoma, employing a hydrogel scaffold derived from the brain-decellularized extracellular matrix in which suspended leukemia cells were embedded, simulating the formation of tumor masses in the brain parenchyma.

An Integrated Arterial Remodeling Hydrogel for Preventing Restenosis After Angioplasty

[Advanced Science] A stent-free anti-stenosis drug coating based on a peptide hydrogel was proposed. The hydrogel was formed by assembling a nitric oxide donor-peptide conjugate as a hydrogelator and encapsulating curcumin during the assembly process.

An Animal Study on the Effectiveness of Platelet-Rich Plasma as a Direct Pulp Capping Agent

[Scientific Reports] Scientists investigated the effectiveness of Platelet Rich Plasma vs. Mineral Trioxide Aggregate as a direct pulp capping agent. 42 teeth from three mongrel dogs were divided into two equal groups.

Rice Grains Integrated with Animal Cells: A Shortcut to a Sustainable Food System

[Matter] The potential of rice grains as cell scaffolds is demonstrated by investigating the interactions between the coating, grains, and cells.

In Vivo Stimulation of Therapeutic Antigen-Specific T Cells in an Artificial Lymph Node Matrix

[Advanced Materials] Researchers created an artificial lymph node matrix, which consisted of an extracellular matrix hydrogel conjugated with peptide-loaded-MHC complex, the co-stimulatory signal anti-CD28, and a tethered IL-2, that could bypass challenges faced by other approaches to activate T cells in situ.

Collagen Networks under Indentation and Compression Behave Like Cellular Solids

[Langmuir] Scientists investigated the mechanical response of collagen-1 networks to local and bulk compressive loads. They compared these results to the behavior of polyacrylamide, a fundamentally different class of hydrogel network consisting of flexible polymer chains.

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