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Extracellular Matrix News
Brain-Decellularized ECM-Based 3D Myeloid Sarcoma Platform: Mimicking Adaptive Phenotypic Alterations in the Brain
[Advanced Healthcare Materials] Researchers presented a novel 3D in vitro model mimicking intracranial myeloid sarcoma, employing a hydrogel scaffold derived from the brain-decellularized extracellular matrix in which suspended leukemia cells were embedded, simulating the formation of tumor masses in the brain parenchyma.
Extracellular Matrix News
An Integrated Arterial Remodeling Hydrogel for Preventing Restenosis After Angioplasty
[Advanced Science] A stent-free anti-stenosis drug coating based on a peptide hydrogel was proposed. The hydrogel was formed by assembling a nitric oxide donor-peptide conjugate as a hydrogelator and encapsulating curcumin during the assembly process.
Extracellular Matrix News
An Animal Study on the Effectiveness of Platelet-Rich Plasma as a Direct Pulp Capping Agent
[Scientific Reports] Scientists investigated the effectiveness of Platelet Rich Plasma vs. Mineral Trioxide Aggregate as a direct pulp capping agent. 42 teeth from three mongrel dogs were divided into two equal groups.
Extracellular Matrix News
Rice Grains Integrated with Animal Cells: A Shortcut to a Sustainable Food System
[Matter] The potential of rice grains as cell scaffolds is demonstrated by investigating the interactions between the coating, grains, and cells.
Extracellular Matrix News
In Vivo Stimulation of Therapeutic Antigen-Specific T Cells in an Artificial Lymph Node Matrix
[Advanced Materials] Researchers created an artificial lymph node matrix, which consisted of an extracellular matrix hydrogel conjugated with peptide-loaded-MHC complex, the co-stimulatory signal anti-CD28, and a tethered IL-2, that could bypass challenges faced by other approaches to activate T cells in situ.
Extracellular Matrix News
Collagen Networks under Indentation and Compression Behave Like Cellular Solids
[Langmuir] Scientists investigated the mechanical response of collagen-1 networks to local and bulk compressive loads. They compared these results to the behavior of polyacrylamide, a fundamentally different class of hydrogel network consisting of flexible polymer chains.