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Cell Therapy News
ADSCs Labeled with SPIONs Tracked in Corpus Cavernosum of Rat and Miniature Pig by MR Imaging and Histological Examination
[Scientific Reports] Scientists explored the feasibility of non-invasively monitoring intracavernous injection of adipose tissue-derived stem cells in rat and miniature pig corpus cavernosum using in vivo magnetic resonance imaging.
ESC & iPSC News
ZFP281 Controls Transcriptional and Epigenetic Changes Promoting Mouse Pluripotent State Transitions via DNMT3 and TET1
[Developmental Cell] Using Zfp281 knockout mouse and degron knockin cell models, investigators identified the direct transcriptional activation of Dnmt3a/3b by ZFP281 in PSCs.
ESC & iPSC News
Characterization of Heterozygous ATTR Tyr114Cys Amyloidosis-Specific Induced Pluripotent Stem Cells
[Heliyon] Investigators took advantage of disease-specific iPS cells and generated & characterized the heterozygous ATTR Tyr114Cys amyloidosis-specific iPS cells, to determine whether Y114C iPS cells could be useful for elucidating the pathogenesis of ATTR Tyr114Cys amyloidosis.
Mammary Cell News
CGA Alleviates LPS-Induced Inflammation and Milk Fat Reduction in BMECs through the NF-κB Signaling Pathway
[Heliyon] Scientists explored whether chlorogenic acid attenuated lipopolysaccharide-induced inflammation and decreased milk fat in bovine mammary epithelial cells.
Newsletters
A Second-Generation eIF4A RNA Helicase Inhibitor Exploits Translational Reprogramming as a Vulnerability in Triple-Negative Breast Cancer
[Proceedings Of The National Academy Of Sciences Of The United States Of America] Researchers developed an orally bioavailable rocaglate-based molecule, MG-002, which hindered ribosome recruitment and scanning via unscheduled and non-productive RNA clamping by the eukaryotic translation initiation factor 4A RNA helicase.
Newsletters
Microbiota of Pregnancy, Placenta and Newborns in the Third Trimester: A Randomized Controlled Study
[Heliyon] Scientists found that the microbiota of pregnant individuals changes in the third trimester. The placental microbiota has its own specific dominant microbiota.