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ADSCs Labeled with SPIONs Tracked in Corpus Cavernosum of Rat and Miniature Pig by MR Imaging and Histological Examination

[Scientific Reports] Scientists explored the feasibility of non-invasively monitoring intracavernous injection of adipose tissue-derived stem cells in rat and miniature pig corpus cavernosum using in vivo magnetic resonance imaging.

ZFP281 Controls Transcriptional and Epigenetic Changes Promoting Mouse Pluripotent State Transitions via DNMT3 and TET1

[Developmental Cell] Using Zfp281 knockout mouse and degron knockin cell models, investigators identified the direct transcriptional activation of Dnmt3a/3b by ZFP281 in PSCs.

Characterization of Heterozygous ATTR Tyr114Cys Amyloidosis-Specific Induced Pluripotent Stem Cells

[Heliyon] Investigators took advantage of disease-specific iPS cells and generated & characterized the heterozygous ATTR Tyr114Cys amyloidosis-specific iPS cells, to determine whether Y114C iPS cells could be useful for elucidating the pathogenesis of ATTR Tyr114Cys amyloidosis.

CGA Alleviates LPS-Induced Inflammation and Milk Fat Reduction in BMECs through the NF-κB Signaling Pathway

[Heliyon] Scientists explored whether chlorogenic acid attenuated lipopolysaccharide-induced inflammation and decreased milk fat in bovine mammary epithelial cells.

A Second-Generation eIF4A RNA Helicase Inhibitor Exploits Translational Reprogramming as a Vulnerability in Triple-Negative Breast Cancer

[Proceedings Of The National Academy Of Sciences Of The United States Of America] Researchers developed an orally bioavailable rocaglate-based molecule, MG-002, which hindered ribosome recruitment and scanning via unscheduled and non-productive RNA clamping by the eukaryotic translation initiation factor 4A RNA helicase.

Microbiota of Pregnancy, Placenta and Newborns in the Third Trimester: A Randomized Controlled Study

[Heliyon] Scientists found that the microbiota of pregnant individuals changes in the third trimester. The placental microbiota has its own specific dominant microbiota.

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