Publication

[Journal For Immunotherapy Of Cancer] Investigators used RNA sequencing to assess whether the recently invented membrane-anchored and tumor-targeted IL-12-armed T cells, which bind cell-surface vimentin on tumor cells, could destroy cancer-associated fibroblasts to disrupt the extracellular matrix.

[Radiation Oncology] Researchers investigated the potential of carbon-ion radiotherapy and isoeffective doses of X-ray radiotherapy to mediate tumor growth inhibition and survival in murine colon adenocarcinoma models in conjunction with neoantigen-specific liposome-formulated mRNA vaccines vaccines, encoding both MHC class I and II-restricted tumor-specific neoantigens.

[Cardiovascular Research] Scientists demonstrated, for the first time, that TNNT2-4Fpolycistronic-NIL gene therapy induces cardiomyocyte cell cycle re-entry in chronic ischemic heart failure and improves left ventricular function and that this salubrious effect is sustained for at least four months.

[Cell Reports] Researchers compared genome-wide replication timing between ESCs, iPSCs, and cells reprogrammed by somatic cell nuclear transfer.

[Stem Cell Research] Investigators report the establishment of three isogenic hiPSC lines generated from normal neonate male skin fibroblasts. Pluripotency was induced using the integration free Sendai virus reprogramming method.

[Current Stem Cell Research & Therapy] The authors investigated the differentiation, morphology and electrophysiological properties of hair cell-like cells derived from DFNA36 patient.