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CD201+ Fascia Progenitors Choreograph Injury Repair

[Nature] Researchers identified a multipotent fibroblast progenitor marked by CD201 expression in the fascia, the deepest connective tissue layer of the skin.

Effects of Green Light-Emitting Diode Irradiation on Hepatic Differentiation of Hepatocyte-Like Cells Generated from Human Adipose-Derived Mesenchymal Cells

[Scientific Reports] Scientists investigated the effect of green LED irradiation on the differentiation of adipocyte-derived mesenchymal cells into hepatocyte-like cells and the mechanism of its action.

BRISC Is Required for Optimal Activation of NF-κB in Kupffer Cells Induced by LPS and Contributes to Acute Liver Injury

[Cell Death & Disease] Researchers investigated the pathophysiological role of BRCC3 isopeptidase complex (BRISC) in acute liver failure using a mice model induced by D-galactosamine plus lipopolysaccharide.

Entirely Noninvasive Outcome Prediction in Central Nervous System Lymphomas Using Circulating Tumor DNA

[Blood] Scientists applied ultrasensitive circulating tumor DNA sequencing to 146 plasma and cerebrospinal fluid samples from 67 patients, with the aim of developing an entirely noninvasive dynamic risk model considering clinical and molecular features of central nervous system lymphoma.

Tumor Cell-Induced Macrophage Senescence Plays a Pivotal Role in Tumor Initiation Followed by Stable Growth in Immunocompetent Condition

[Journal For Immunotherapy Of Cancer] Researchers identified one of the requirements for tumor-initiating cells in immunocompetent animals. In addition, they have showed that tumor growth could be inhibited by externally administered nicotinamide mononucleotide against macrophage senescence-like state.

Extended Exposure to Low Doses of Azacitidine Induces Differentiation of Leukemic Stem Cells through Activation of Myeloperoxidase

[Haematologica] In leukemic stem cell (LSC) models, the extended dose of azacitidine induced differentiation and depleted CD34+CD38- LSCs.

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