Publication

[Nature Medicine] MAESTRO-NAFLD-1 was a 52-week randomized, double-blind, placebo-controlled phase III trial evaluating the safety of resmetirom in adults with nonalcoholic fatty liver disease (NAFLD) and presumed nonalcoholic steatohepatitis.

[Acta Pharmacologica Sinica] Scientists investigated the mechanisms of occurrence and development of acute liver injury (ALI) in lipopolysaccharide-induced ALI mice.

[Advanced Healthcare Materials] In vitro, zinc extraction promoted the proliferation and migration of HUVECs and upregulated the key gene for tube formation HIF-1α and VEGF-A, with a peak concentration of 22.5 μм.

[Biomedicine & Pharmacotherapy] Researchers investigated the potential protective effects of 5-Bromo-3,4-dihydroxybenzaldehyde on diabetic retinopathy using primary human retinal vascular endothelial cells and retinal tissue explants.

[EMBO Reports] In vitro, adolescent peripheral blood mononuclear cells produce more cytokines, priming A549 cells for stronger interferon responses to SARS-CoV-2.

[Nature Communications] Researchers showed that a llama-derived nanobody M4 neutralized multiple GII.4 variants with high potency in human intestinal enteroids.