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Muscle Cell News
Spatiotemporal Cell Junction Assembly in Human iPSC-CM Models of Arrhythmogenic Cardiomyopathy
[Stem Cell Reports] The authors built bioengineered platforms using genetically modified human induced pluripotent stem cell-derived cardiomyocytes (hiPSC-CMs) to model the early spatiotemporal process of cardiomyocyte junction assembly in vitro.
Muscle Cell News
Integrative Analysis of DNA Methylome and Transcriptome Reveals Epigenetic Regulation of Bisphenols-Induced Cardiomyocyte Hypertrophy
[Ecotoxicology and Environmental Safety] Researchers performed RNA-seq and reduced representation bisulfite sequencing to profile the landscapes of bisphenol-induced cardiotoxicity and to determine the key roles of DNA methylation in the transcription.
Muscle Cell News
The Kisspeptin-1 Receptor Antagonist Peptide-234 Aggravates Uremic Cardiomyopathy in a Rat Model
[Scientific Reports] Scientists investigated the effects of the kisspeptin receptor antagonist peptide-234 on the development of uremic cardiomyopathy.
Muscle Cell News
Repeated Witness Social Stress Causes Cardiomyocyte Contractile Impairment and Intracellular Ca2+ Derangement in Female Rats
[Physiology & Behavior] Researchers investigated the effects of repeated exposure to witness social defeat stress on cardiomyocyte contractile function and intracellular Ca2+ homeostasis in young adult wild-type Groningen female rats.
Muscle Cell News
TET1 Regulates Skeletal Stem Cell (SSC) Mediated Cartilage Regeneration
[Arthritis & Rheumatology] The authors investigated the differences in SSC lineage tree and differentiation potential in neonatal and adult Tet1+/+ and Tet1-/- mice, with and without injury and upon osteoarthritis induction and progression.
Muscle Cell News
Dysfunctional Endocannabinoid CB1 Receptor Expression and Signaling Contribute to Skeletal Muscle Cell Toxicity Induced by Simvastatin
[Cell Death & Disease] Scientists explored the role of the endocannabinoid system during muscle toxicity induced by simvastatin.