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Chemokines As Possible Therapeutic Targets in Metastatic Melanoma

[Cancer Medicine] The authors focus on the role of chemokines in melanoma and possible therapeutic strategies to alter chemokine activation and subsequently inhibit the activation of signaling cascades that may promote metastasis.

Cooperation of TGF-β and FGF Signaling Pathways in Skin Development

[Cell Proliferation] Scientists provide evidence of the role of TGF-β and fibroblast growth factor (FGF) signaling pathways in the development of different skin layers, especially the disparate dermis of different body regions.

Breakthrough Treatments for Accelerated Wound Healing

[Science Advances] The authors summarize advances in the development of novel drug, biologic products, and biomaterial therapies for wound healing for marketed therapies and those in clinical trials.

Fetal Liver Development and Implications for Liver Disease Pathogenesis

[Nature Reviews Gastroenterology & Hepatology] The authors discuss the emergence of hepatic parenchymal and non-parenchymal cells, advances that have been made in in vitro modelling of liver development and draw parallels between developmental and pathological processes.

Protein Glycosylation Alterations in Hepatocellular Carcinoma: Function and Clinical Implications

[Oncogene] Scientists summarize the functional importance, molecular mechanism, and clinical application of protein glycosylation alterations in HCC.

Involvement of CXCL12/CXCR4 Axis in Colorectal Cancer: A Mini-Review

[Molecular Biology Reports] The authors review emerging data and correlations between CXCL12/CXCR4 axis in colorectal cancer, the implications for cancer progression, and possible therapeutic strategies that exploit this system.

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