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Review
Mesenchymal Cell News
Role and Mechanisms of Histone Methylation in Osteogenic/Odontogenic Differentiation of Dental Mesenchymal Stem Cells
[International Journal of Oral Science] Scientists provide an overview of the functions of epigenetic histone methylation at H3K4, H3K9, and H3K27 in the regulation of osteo-/odontogenic differentiation and renewal of dental MSCs in both non-inflammatory and inflammatory microenvironments.
Hematopoiesis News
How I Treat Chronic Myeloid Leukemia in Children and Adolescents
[Blood] The authors present three cases commonly encountered in pediatric chronic myeloid leukemia, their challenges and relevant issues as well as recommended managements.
Hematopoiesis News
Emerging T Cell Lymphomas after CAR T-Cell Therapy
[Leukemia] Scientists integrate the latest evidence on chimeric antigen receptor T cell lymphomas, dissect their diagnostic as well as clinical features, and explore the molecular mechanisms that may drive their emergence.
Hematopoiesis News
Current Landscape of Vector Safety and Genotoxicity after Hematopoietic Stem or Immune Cell Gene Therapy
[Leukemia] Investigators summarize current clinical information and revisit genotoxicity risks following ex-vivo gene modification of HSC and T cells.
Muscle Cell News
Molecular Gatekeepers of Endogenous Adult Mammalian Cardiomyocyte Proliferation
[Nature Reviews Cardiology] Investigators explore the molecular pathways underlying these core mechanisms and how their manipulation can reactivate the cell cycle in cardiomyocytes, potentially contributing to cardiac repair.
Neural Cell News
Microglia Heterogeneity, Modeling and Cell-State Annotation in Development, and Neurodegeneration
[Nature Neuroscience] Investigators provide an overview of mouse and human microglial diversity encompassing aspects of development, neurodegeneration, sex, and central nervous system regions.