Review

[Hormones] An in-depth study of the role of exosomes in the pathogenesis of diabetes may provide a novel means of diagnosing and treating diabetes. Scientists detail how exosome is involved in the development of diabetes.

[Nature Reviews Drug Discovery] The authors discuss concerns, specifically how cell tropism and tissue distribution of mRNA and lipid nanoparticles can lead to toxicity, and their possible reactogenicity.

[Cell Death Discovery] In the face of the current situation of poor therapeutic effects of tumor immunotherapy, combined application of targeted immune cell fatty acid metabolism seems to have good therapeutic potential, which is blocked at immune checkpoints.

[Nature Immunology] The authors discuss how T cells integrate nutrient sensing with activating stimuli to shape their differentiation and sensitivity to metabolites.

[Journal of Molecular and Cellular Cardiology] Scientists summarize the research progress on the mechanisms and challenges of mesenchymal stromal cells and induced pluripotent stem cell-derived cardiomyocytes in post-MI heart repair.

[Journal Of Investigative Dermatology] The authors summarize the current update on IL-36 cytokines in inflammatory skin diseases.