Review

[European Journal Of Immunology] Scientists summarize recent reports on patient derived human small intestinal and colonic organoids and highlight how these models have been used to study intestinal epithelial functions.

[Nature Reviews Neurology] Scientists examine the roles of large and small vessel disease in vascular cognitive impairment and dementia, considering the underlying pathophysiological processes that lead to vascular brain injury.

[International Journal of Biological Macromolecules] Scientists review recent advances in natural biomaterials-based glioblastoma organoid models, as in vitro experimental platforms to simulate glioblastoma tumor biology and response to tested drugs.

[Biomedicine & Pharmacotherapy] The authors summarize the current research progress and clinical implementation of BRCA and BRCAness in targeted treatments for the DNA repair pathway.

[Stem Cells Translational Medicine] Investigators propose prospective mechanisms of action of Wharton's jelly-MSCs that may be mediating their observed capability to preserve β-cell function and prevent type 1 diabetes progression and provide recommendations for further investigations in clinical settings.

[APMIS] The authors summarize the structure, characteristics, and physiological functions of microfibrillar-associated protein 4 (MFAP4) and the importance of MFAP4 in various fibrotic diseases.