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Monocyte-to-HDL Ratio Revealed as Key Indicator of Endothelial Dysfunction in Patients With Diabetes

[Physcians Weekly] A cross-sectional study identified the monocyte-to-HDL ratio (MHR) as an indicator of poor endothelial dysfunction in diabetic patients, with each 10% increase in MHR associated with a 35% rise in endothelial dysfunction after adjusting for various factors.

EPA Scraps Plan to End Mammal Testing by 2035

[Science Insider] The US Environmental Protection Agency (EPA) has abandoned a controversial plan to phase out all use of mammals to test the safety of chemicals by 2035. The hard deadline—imposed in 2019 to accelerate a move toward nonanimal models such as computer programs and “organs on a chip”—made EPA unique among US federal agencies.

2023 Nobel Prize Winner Drew Weissman, MD, PhD, Reflects on the Value of Basic Science Research

[AAMC] The laureate discusses the groundbreaking work that led to COVID-19 vaccines, why he persisted with RNA research despite repeated setbacks, and the value of scientists working in-person.

Needle-Free Vaccine Candidate Promises Improved, Longer-Term Immunity Against COVID-19

[NUS News] Researchers from Duke-NUS Medical School have discovered a new vaccine candidate that can be delivered through the nose in the form of a spray that promises better and longer-lasting immunity against COVID-19 compared to the conventional COVID-19 vaccine administered subcutaneously.

USask Student Works to Crack the Code of Long COVID

[Sasktoday] University of Saskatchewan (USask) graduate student Ethan Jansen is on a mission to help those affected by emerging global viruses and has joined a team of Canadian researchers leading the charge to discover more about the long-term effects of COVID-19.

Analysis of Brain Tumor Blood Vessels Yields a Candidate Therapy—And a Platform to Find More

[EurekAlert] A Ludwig Cancer Research study has generated a granular portrait of how the cellular and molecular components of the blood vessels that feed brain metastases of melanoma and lung and breast cancers differ from those of healthy brain tissue, illuminating how they help shape the internal environment of tumors to support cancer growth and immune evasion.

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