Publication

[Scientific Reports] Researchers determined if the consumption of a high-fat high-sucrose (HFS) diet, starting in the post-weaning period, led to changes in skeletal muscle morphology and mechanics after 14 weeks on the HFS diet.

[Journal of Advanced Research] Dual-luciferase reporter gene assay was performed to validate two competing endogenous RNA axes, hsa_circ_0001402/miR-183-5p/FKBP prolyl isomerase like and hsa_circ_0001402/miR-183-5p/beclin 1.

[Cellular and Molecular Life Sciences] Investigators showed that circACTA2 was down-regulated in human intimal hyperplasia. circACTA2 overexpression in circACTA2 transgenic mice significantly decreased the neointimal hyperplasia induced by vascular injury.

[Journal Of Thoracic And Cardiovascular Surgery] Non-dilated aortic samples were harvested intra-operatively from individuals with normal aortic valves or those with either predominant aortic stenosis or aortic regurgitation.

[Scientific Reports] Using a pharmacological target network interaction analysis, 151 common targets and a protein–protein interaction network were identified containing the top 10 hub genes.

[Cell Metabolism] Using RNA-seq and CUT&Tag chromatin profiling, researchers found that induction of hexokinase 2 expression in activated hepatic stellate cells was required for induced gene expression by histone lactylation but not histone acetylation.