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Mammary Cell News
NFYA Promotes Malignant Behavior of Triple-Negative Breast Cancer in Mice through the Regulation of Lipid Metabolism
[Communications Biology] Scientists demonstrated that NFYAv1, a long-form variant, upregulated the transcription of essential lipogenic enzymes ACACA and FASN to enhance the malignant behavior of TNBC.
Mammary Cell News
Synergistic Cytotoxic Effects of an Extremely Low-Frequency Electromagnetic Field with Doxorubicin on MCF-7 Cell Line
[Scientific Reports] The authors investigated the potential cytotoxic effect of doxorubicin at low concentrations in combination with extremely low-frequency electromagnetic fields. The breast cancer cell line MCF-7 was examined for oxidative stress, cell cycle, and apoptosis.
Mammary Cell News
Insulin-Like Growth Factor Binding Protein-3 Induces Senescence by Inhibiting Telomerase Activity in MCF-7 Breast Cancer Cells
[Scientific Reports] Investigators showd that insulin-like growth factor binding protein-3 induced cellular senescence via suppression of the telomerase activity, thereby inhibiting MCF-7 breast cancer cell proliferation.
Mammary Cell News
Pharmacological Inhibition of Neuropeptide Y Receptors Y1 and Y5 Reduces Hypoxic Breast Cancer Migration, Proliferation, and Signaling
[BMC Cancer] Researchers measured the effects of neuropeptide Y (NPY) 1R and NPY5R antagonists in normoxia and hypoxia on migration, proliferation, invasion, and signaling in 2D and 3D models of breast cancer cell lines MDA-MB-231 and MCF7.
Newsletters
Optogenetic Engineered Umbilical Cord MSC-Derived Exosomes for Remodeling of the Immune Microenvironment in Diabetic Wounds and the Promotion of Tissue Repair
[Journal of Nanobiotechnology] Researchers discussed the effects and mechanisms of eNOS-rich umbilical cord MSC exosomes modified by genetic engineering and optogenetic techniques on diabetic chronic wound repair.
Newsletters
The Transposable Element-Derived Transcript of LIN28B Has a Placental Origin and Is Not Specific to Tumours
[Molecular Genetics and Genomics] Scientists discovered co-expression of some transposable elements and oncogenes in human embryonic stem cells and first trimester and term placental tissues.