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Hematopoiesis News
Circadian Disturbances by Altering the Light–Dark Cycle Negatively Affects Hematopoietic Function of Bone Marrow in Mice
[FASEB Journal] The authors exposed C57bl/6j mice to repeated reversed light–dark cycles for 90 days to research the effects of circadian disturbance on bone marrow hematopoietic function.
Hematopoiesis News
Pre-frailty after Blood or Marrow Transplantation and the Risk of Subsequent Mortality
[Leukemia] Investigators examined the prevalence, risk factors, and association between pre-frailty and subsequent mortality after blood or marrow transplantation.
Mesenchymal Cell News
Efficacy and Safety of Mesenchymal Stem Cell Therapy for Ovarian Aging in a Mouse Model
[Stem Cell Research & Therapy] Two common sources of MSCs, umbilical cord-derived MSCs and adipose tissue-derived MSCs, were orthotopically transplanted into a mouse model of ovarian aging to evaluate their therapeutic effects.
Mesenchymal Cell News
Mesenchymal Stem Cell-Derived Extracellular Vesicles Alleviate Brain Damage Following Subarachnoid Hemorrhage via the Interaction of miR-140-5p and HDAC7
[Molecular Neurobiology] Researchers explored the role of miR-140-5p delivered by MSC-extracellular vesicles in mitigating brain damage following subarachnoid hemorrhage (SAH). Serum from SAH patients and healthy individuals was analyzed for miR-140-5p and cAMP levels.
Mesenchymal Cell News
Exosomes From Adipose-Derived Mesenchymal Stem Cell Improve Diabetic Wound Healing and Inhibit Fibrosis via miR-128-1-5p/TGF-β1/Smad Axis
[Molecular And Cellular Endocrinology] In vitro, adipose stem cell-derived exosomes significantly enhanced proliferation and migration of rat skin fibroblasts while reducing the expression of TGF-β1 and α-SMA.
Mesenchymal Cell News
Regulatory T Cell-Derived Exosome Mediated Macrophages Polarization for Osteogenic Differentiation in Fracture Repair
[Journal Of Controlled Release] Investigators constructed regulatory T cell-derived exosomes for the treatment of fracture. The obtained exosomes displayed a spheroid shape with a hydrated particle size of approximately 130 nm.