Publication

[Biomacromolecules] Cell culture experiments showed that a novel composite fiber membrane had high cell viability, promoting the proliferation and adhesion of human umbilical vein endothelial cells and inducing a contractile phenotype in human umbilical artery smooth muscle cells.

[APL Bioengineering] Using DEFLCT, researchers exposed primary human airway smooth muscle cell-derived microtissues to a panel of six inflammatory cytokines present in the asthmatic niche, identifying TGF-β1 and IL-13 as inducers of a hypercontractile phenotype.

[Journal Of Cellular Biochemistry] Investigators determined the effect of co-activation of MasR and particulate guanylate cyclase receptor (pGCA) pathways by synthesizing novel peptides in oxidative stress-induced vascular smooth muscle cells and endothelial cells.

[Nature Communications] Informed by proteomics analyses of FACS-sorted inflammasomes, the authors identify a protein complex modulating inflammasome activity on endosomes.

[Bone Research] Scientists confirmed that glucocorticoid-induced apoptosis of bone microvascular endothelial cells was a pre-event in the pathogenesis and progression of steroid-induced osteonecrosis of the femoral head (SONFH).

[Nature Cardiovascular Research] By analyzing single and compound genetic mutants for all Notch signaling members, researchers found significant differences in the way ligands and receptors regulate liver vascular homeostasis.