Publication

[Cancer Research] Mass spectrometry–based analyses demonstrated that salt-inducible kinase 1 (SIK1) boundAKT and underwent AKT-mediated phosphorylation, which compromised SIK1 tumor-suppressive functions.

[British Journal of Pharmacology] A miR-9 knockout mode of mouse breast cancer MMTV-PyMT model combined with different human breast cancer cell lines were used to evaluate the effects of miR-9 on breast cancer initiation, progression, and metastasis.

[Breast Cancer Research] Investigators explored the impacts of doublecortin-like kinase 1 (DCLK1) on tumor cells as well as their immune microenvironment in triple-negative breast cancer (TNBC) and potential therapeutic strategies for TNBC patients with high DCLK1 expression.

[Biology Direct] Researchers found through abundant in vitro and in vivo> experiments which the expression of TM4SF1 was positively correlated with the progression and cancer stemness of hepatocellular carcinoma (HCC).

[CNS Neuroscience & Therapeutics] Scientists bserved the interaction between glioma stem cells and primary cultured dendritic cells (DCs) in a dual-color tracing model, monoclonal and continuously passaged highly proliferative DCs, and named transformed DCs.

[Aging] Ubiquitination modification patterns in low-grade glioma patients and corresponding characteristics of tumor immune traits, CSC stemness, and cellular senescence were evaluated via a comprehensive analysis of 20 ubiquitination modification regulators.