Publication

[Transplantation And Cellular Therapy] The authors explored the potential application of human cord blood derived-multipotent stem cells to control donor alloreactive responses involved in allogeneic hematopoietic cell transplantation, which often results in acute graft-vs-host disease.

[Nucleic Acids Research] Researchers stimulated the retinoic acid (RA) pathway by treating zebrafish embryos with all-trans-RA and used a combination of RNA-seq, ATAC-seq, ChIP-seq and HiChIP to gain insight into the molecular mechanisms by which exogenously induced RA signaling controlled gene expression.

[Journal Of Biological Chemistry] Administration of Go6983 increased Prdm14 expression mainly through the inhibition of PKCδ. High constitutive expression of Prdm14 phenocopied the ability of Go6983 to maintain` mouse ESC stemness in the absence of self-renewal-promoting cytokines.

[Life Science Alliance] Scientists showed that the degree of coordination of allelic bursting differed among genes, and alleles of many reprogramming-related genes burst in a highly coordinated fashion.

[Genome Biology] The authors employed an unbiased chromatin immunoprecipitation-based proteomic technique to identify endogenous androgen receptor (AR) interacting co-regulatory proteins in estrogen receptor positive and negative models of breast cancer to gain new insight into mechanisms of AR signaling in this disease.

[Small] Cellular interaction and effects of Hexagonal boron nitride nanosheets was investigated in alveolar epithelial cells cultured on porous inserts and exposed under air−liquid interface conditions for 24 hours.