Publication

[Jama Oncology] The Phase II nonrandomized clinical trial enrolled 42 patients with uncommon EGFR mutations, of whom 40 were eligible.

[Biomedicine & Pharmacotherapy] Investigators observed that bleomycin induced enhanced mitophagy accompanied by increased mitochondrial ROS content in the murine alveolar epithelial cell line MLE12.

[Journal of Translational Medicine] CCK8 assays, EdU assays, Scratch assay and Transwell migration assay were conducted to detect the role of circTENM3 in prostate cancer cells in vitro.

[Cell Reports] Investigators demonstrated that early postnatal growth of the pancreas unexpectedly involves massive acinar cell elimination.

[Heliyon] Researchers examined the CCCTC-binding factor (CTCF) function in pancreatic cancer (PC) and discovered that CTCF expression in PC tissues was significantly raised compared to neighboring healthy tissues.

[iScience] Unbiased transcriptome and metabolome analyses showed that PDAC cells with disrupted KRASG12D-NRF2 signalling (NRF2−/− cells) shift from aerobic glycolysis to metabolic pathways fed by amino acids.