Publication

[Journal Of Investigative Dermatology] Investigators achieved highly efficient COL7A1 editing in primary recessive dystrophic epidermolysis bullosa keratinocytes and fibroblasts from two patients homozygous for the c.6508C>T mutation.

[Experimental Dermatology] Researchers validated different engineered immortalized cell lines created from primary human keratinocytes as model systems to study epidermal function.

[Journal Of Physiology And Biochemistry] Human adipose tissue-derived exosomes incubation increased keratinocytes and fibroblast proliferation, migration, and extracellular matrix accumulation.

[Free Radical Biology And Medicine] Scientists compared the impact of an active form of vitamin D3 on mitochondrial morphology and bioenergetics in human squamous cell carcinoma and immortalized HaCaT keratinocytes.

[ACS Nano] Investigators demonstrated that MSC-derived apoptotic vesicles (apoVs) were promising therapeutic agents for bone regeneration. However, clinical translation of MSC-derived apoVs had been hindered due to cell expansion and nuclear substance.

[Biochimica Et Biophysica Acta-Molecular Basis Of Disease] Researchers identified enhancers-mediated gene FOXO3 promoting MSC adipogenic differentiation by activating autophagy.