Publication

[Nature Communications] The authors analyzed acute graft-versus-host disease phenotypes and clinical classifications in depth in large, multicenter cohorts involving 3019 patients, and addressed prevailing gaps by developing data-driven models.

[Blood Cancer Journal] Scientists showed that co-expression of Srsf2P95H mutant reduced red blood cell, neutrophil, and platelet counts,and attenuated splenomegaly, but did not induce bone marrow fibrosis in the Jak2V617F/+ mice.

[Molecular Cancer Therapeutics] Scientists monitored cell viability in organoids, tumor volume, and PSA secretion in patient-derived xenografts and analyzed cell cycle and signaling pathway alterations.

[Advanced Science] Investigators demonstrated that tumor-associated macrophages-secreted taurine suppressed ferroptosis in prostate cancer by activating the Liver X receptor alpha/Stearoyl-Coenzyme A desaturase 1 pathway.

[Oncogene] Scientists observed changes which affected proliferation, colony formation, and 3D-spheroid growth of multiple epithelial prostate cancer cell models.

[Nature Communications] The authors demonstrated that the RNA-binding protein ELAVL3 was specifically upregulated in neuroendocrine prostate cancer and that overexpression of ELAVL3 alone was sufficient to induce the neuroendocrine phenotype in prostate adenocarcinoma.