Publication

[Stem Cell Research & Therapy] Investigators performed an integrated clinical characteristic and nutritional risk factor analysis and established a predictive model that could be used to identify umbilical cord blood transplantation recipients with poor overall survival. Internal validation was performed by using the bootstrap method with 500 repetitions.

[Stem Cell Reviews And Reports] Scientists compared the heterogeneity of the human MSCs derived from bone marrow umbilical cord, and adipose tissue in accelerating wound healing and promoting angiogenesis and explored the underlying mechanism.

[International Journal Of Biological Macromolecules] Investigators proposed to use genipin as an efficient cross-linking agent to significantly improve the elasticity and the enzymatical stability of the Wharton's jelly matrix.

[Nature Medicine] Investigators identified the safety and efficacy of cell injections from autologous bone marrow aspirate concentrate, autologous adipose stromal vascular fraction and allogeneic human umbilical cord tissue-derivedMSCs, in comparison to corticosteroid injection.

[Life Sciences] The authors assessed the regulatory effects of human umbilical MSCs on the gut microbiota, T lymphocyte subpopulations and related immune cytokines in the trinitrobenzene sulfonic acid-induced inflammatory bowel diseases model.

[Nature Communications] Scientists showed that standard of care therapy caused DNA damage and toxic PARP1 trapping upon generation of a functional BRCAness phenotype, leading to increased histone parylation and reduced H3K9 acetylation, resulting in transcriptional blockage and cell death.