Publication

[Journal Of Translational Medicine] The microarray dataset GSE12884 was analyzed to identify the differentially expressed lncRNAs in adipose-derived mesenchymal stem cells under normoxia and hypoxia. The expression of the key genes was detected using qRT-PCR, western blot assay, and immunofluorescence staining.

[Nature Communications] Scientists identified two T cell receptors (TCRs) specific for the 9-mer KRAS-G12V mutant neoantigen in the context of HLA-A*11:01. The TCR-T cells are constructed and display cytokine secretion and cytotoxicity upon co-culturing with varied tumor cells expressing the KRAS-G12V mutation.

[Annals Of Hematology] Researchers conducted a Phase Ib trial testing time-limited therapy with different immunotherapy doublets targeting 4-1BB, OX-40, and PD-L1 in combination with rituximab among patients with relapsed/refractory grade 1–3A FL.

[Heliyon] Tendon-derived stem cells were isolated and characterized. In vitro, the levels of immunoregulatory-related cytokines such as IL-1β, IL-6, IL-10, and TGF-β secreted by 1βUC-MSCs and unprimed umbilical cord-MSCs was measured.

[European Journal Of Vascular And Endovascular Surgery] C57BL/6N male mice were fed with a selenium (Se) deficient, Se adequate, or Se supplemented diet for eight weeks. Subsequently, an AA murine model was established using angiotensin II for four weeks plus β-aminopropionitrile for the first two weeks.

[Scientific Reports] Scientists demonstrated that empagliflozin administration under ad libitum feeding did not cause weight loss but did increase transcripts of the key nutrient sensors.