Publication

[Nature Biotechnology] Scientists reported the generation of human trunk-like structures that modeled the co-morphogenesis, patterning and differentiation of the human spine and spinal cord.

[Advanced Healthcare Materials] Researchers developed a customized bioreactor that allowed dynamic loading of periodontal ligament-derived fibroblasts. A collagen-based hydrogel mixture was optimized to maintain structural integrity and constant cell growth during stretching.

[Cell Systems] Investigators developed a microwell-based method that enabled high-throughput quantification of image-based parameters for organoids grown from single cells, which could further be retrieved from their microwells for molecular profiling.

[Stem Cell Reports] To investigate in vitro neovascularization and various 3D microenvironmental approaches, scientists designed a comprehensive single-cell transcriptomic study.

[Frontiers in Cellular Neuroscience] Researchers explored the efficiency and reliability of a differentiation method, called CYST protocol, that facilitated retina generation by forming neuroepithelial cysts from hiPSC clusters.

[Matter] Researchers introduced chitosan scaffolds as an alternative culture platform to costly animal-sourced feeders, Matrigel, and Geltrex for human neural stem cell expansion.