Publication

[Journal Of Nanobiotechnology] The researchers' scaffold featured a distinct layered nano-hydroxyapatite/chitosan layered composite scaffold composite structure with intervals ranging from 50 to 200 μm, which provided a conducive environment for human bone marrow MSCs adhesion and proliferation, allowing for in situ growth of newly formed bone tissue.

[Journal Of Nanobiotechnology] Adipose-derived stem cells (ADSCs) transfected with small interfering RNA and HIF-1α overexpression plasmid were established to investigate the proliferation, migration, adhesion, and osteogenic capacity of ADSCs and the angiogenic ability of human umbilical vein endothelial cells.

[Stem Cells] Scientists investigate the role of hydrogen sulfide in mesenchymal stem cell aging and the underlying mechanism, and to provide novel insights into stem cell therapies in elderly people bone marrow MSCs were isolated from young mice and from old mice.

[Advanced Science] The immunosuppressive properties of aged MSCs were found to be repressed. The impaired immunosuppressive function of aged MSCs was associated with lower expression of the Hippo effector Yes-associated protein 1 and its target gene signal transducer and activator of transcription 1.

[Cell Death Discovery] Parental and JQ1-resistant SUM149 and SUM159 exhibited a stem cell-like and embryonic diapause (SCLED) cell state as well as a transitional cell state between the SCLED state that is present in both treatment naïve and JQ1 treated cells, and a number of JQ1 resistant cell states.

[Oncogene] Researchers demonstrated that undifferentiated cells are more sensitive to ferroptosis than differentiated cells, and cystine transporter SLC7A11 protein is highly up-regulated by deubiquitinase DUBA in differentiated cells.