Review

[Journal Of Crohns & Colitis] The authors review the current literature about ECM remodeling by matrix metalloproteinase in intestinal fibrosis and their potential role as biomarkers for disease progression or druggable targets.

[Nature Biotechnology] As the numbers of approved products and indications continue to grow, new strategies to increase cell-manufacturing capacity are urgently needed to ensure patient access. Distributed manufacturing at the point of care or at other local manufacturing sites would go a long way toward meeting the rising demand.

[Gene Therapy] Scientists describe the current state of banking of gestational tissues and their derived perinatal stem cells, discusses why the changes in birth trends and delivery methods could affect gestational tissue banking practices

[Current Opinion In Oncology] The authors provide a brief summary on the clinical relevance of recent research findings, which could soon pave the way towards a more personalized and targeted management of SCLC patients.

[Trends In Cell Biology] The authors provide an overview of emerging kidney organoid and tubuloid models and focus on the most recent developments that utilize their functional capabilities.

[Oncogenesis] The authors discuss recent genetic, epigenetic, and environmental findings related to colitis-associated colorectal cancer pathogenesis in the past five years, with a focus on unbiased, high-resolution genetic profiling of non-dysplastic field cancerization in the context of inflammatory bowel disease.