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Review

An Emerging Double-Edged Sword Role of Ferroptosis in Cardiovascular Disease (Review)

[International Journal of Molecular Medicine] The authors provided an in‑depth analysis of advancements in understanding the mechanisms underlying ferroptosis. The present manuscript summarized the interplay between ferroptosis and cardiovascular diseases, highlighting its dual roles in these conditions.

Endothelial Heterogeneity in Bone Marrow: Insights Across Development, Adult Life, and Leukemia

[Leukemia] The authors highlight key milestones and recent advances in understanding vascular heterogeneity within bone marrow microenvironment during development, adulthood, and aging.

HSD3B1, Prostate Cancer Mortality, and Modifiable Outcomes

[Nature Reviews Urology] Multiple clinical studies, including data derived from prospective Phase III studies, have linked adrenal-permissive allele inheritance to inferior clinical responses to androgen deprivation therapy and increased mortality, but reversal is possible with upfront adrenal androgen blockade.

Recent Development of Fibrous Hydrogels: Properties, Applications and Perspectives

[Advanced Science] Scientists review the main advantages of fibrous hydrogels, including enhanced mechanical properties, high conductivity, high antimicrobial and anti-inflammatory properties, stimulus responsiveness, and an ECM-like structure.

A Three-Layer Perspective on miRNA Regulation in β Cell Inflammation

[Trends In Endocrinology and Metabolism] Advances in RNA sequencing have revealed miRNA variants, called isomiRs, that arise from alternative processing or modifications of canonical sequences. Scientists discuss the potential link between cellular stresses and isomiR biogenesis, and how this association could improve our knowledge of islet inflammation and dysfunction.

Targeting Chaperone-Mediated Autophagy in Neurodegenerative Diseases: Mechanisms and Therapeutic Potential

[Acta Pharmacologica Sinica] Scientists illuminate the molecular mechanisms and regulatory pathways governing chaperone-mediated autophagy (CMA). They discuss the potential roles of CMA in maintaining neuronal proteostasis and modulating neuroinflammation mediated by glial cells.

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