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Review

Recent Advances in Bacterium-Based Therapeutic Modalities for Melanoma Treatment

[Advanced Healthcare Materials] The authors provide a summary of the state-of-the-art bacterium-based anti-melanoma modalities, which are categorized according to their unique functional merits, including tumor-specific cytotoxins, tumor-targeted drug delivery platforms, and immune-stimulatory agents.

Structural Extracellular Matrix-Mediated Molecular Signaling in Wound Repair and Tissue Regeneration

[Biochimie] Through studying ECM dynamics, researchers have discovered molecular signaling pathways that demonstrate how the ECM influences protein patterns and open up more possibilities for developing therapeutics that target the ECM to enhance wound repair and tissue regeneration.

Plant-Based Diets and Urological Health

[Nature Reviews Urology] Epidemiological evidence shows that a diet higher in plant-based and lower in animal-based food is associated with a lower risk of aggressive prostate cancer and better quality-of-life scores than a diet with less plant-based and more animal-based food.

Signaling Pathways Involved in Colorectal Cancer: Pathogenesis and Targeted Therapy

[Signal Transduction and Targeted Therapy] The authors discuss the molecular hallmarks of colorectal cancer (CRC), including the genomic, epigenomic, and microbial features of CRC to highlight the role of signal transduction in the orchestration of the tumorigenic process.

Therapeutic Applications and Challenges in Myostatin Inhibition for Enhanced Skeletal Muscle Mass and Functions

[Molecular and Cellular Biochemistry] The authors detail the mechanisms behind myostatin’s function and the various inhibitors that have been tested preclinically and clinically.

Mechanical Strategies to Promote Vascularization for Tissue Engineering and Regenerative Medicine

[Burns & Trauma] Scientists summarizes the influence and contribution of both scaffold-based and external stimulus-based mechanical strategies for vascularization in tissue engineering and elucidates the underlying mechanisms involved.

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