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Using Human Induced Pluripotent Stem Cell-Derived Liver Cells to Investigate the Mechanisms of Liver Fibrosis In Vitro

[Biochemical Society Transactions] The authors outline the differentiation system of liver non-parenchymal cells from human induced pluripotent stem celld (hiPSCs) and development of in vitro liver disease models using hiPSC-derived liver cells.

Circadian Regulation of Liver Function: From Molecular Mechanisms to Disease Pathophysiology

[Nature Reviews Gastroenterology & Hepatology] Scientists cover the molecular, cellular and organismal aspects of various liver pathologies from a circadian viewpoint, and in particular how circadian dysregulation has a role in the development and progression of these diseases.

Monocyte Regulation by Gut Microbial Signals

[Trends In Microbiology] The authors discuss the newer concepts of regulation of monocyte homeostasis and function by gut microbial signals during steady state and inflammation, and highlight the therapeutic potential of microbial signal-based approaches for modulation in the context of various diseases.

Inflammation and Aging: Signaling Pathways and Intervention Therapies

[Signal Transduction And Targeted Therapy] Scientists discuss inflammaging at the molecular, cellular, organ, and disease levels, and review current aging models, the implications of cutting-edge single cell technologies, as well as anti-aging strategies.

CircRNAs in Colorectal Cancer: Potential Biomarkers and Therapeutic Targets

[Cell Death & Disease] Up-to-date research on the role of circRNAs in colorectal cancer (CRC) was examined, focusing on their potential application in CRC diagnosis and targeted therapy, which would advance the knowledge of the functions of circRNAs in the development and progression of CRC.

Recent Advances microRNAs and Metabolic Reprogramming in Colorectal Cancer Research

[Frontiers in Oncology] Scientists review the relationship between colorectal cancer and microRNA expression, and provide strategies for exploring potential options for colorectal cancer treatment.

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