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Biomaterials for Chimeric Antigen Receptor T Cell Engineering

[Acta Biomaterialia] The authors focus on the engineering of non-viral gene delivery nanoparticles for transducing CAR into T cells ex vivo/in vitro or in vivo.

Vascular Contribution to Lung Repair and Fibrosis

[American Journal of Respiratory Cell and Molecular Biology] The authors summarize current findings related to lung vascular repair and regeneration and provides recent insights into the vascular abnormalities associated with the development of persistent lung fibrosis.

Pro-Inflammatory Cytokines Mediating Senescence of Vascular Endothelial Cells in Atherosclerosis

[Fundamental & Clinical Pharmacology] Scientists summarize and focus on the pro-inflammatory cytokines which often induce the senescence of vascular endothelial cells (VECs) and the molecular mechanisms of these pro-inflammatory cytokines inducing senescence of VECs.

Stem Cell-Derived Exosomes: Emerging Therapeutic Opportunities for Wound Healing

[Stem Cell Research & Therapy] The authors focus on the specific roles and mechanisms of different mesenchymal stem cells-exosomes in wound healing, as well as the current limitations and various perspectives.

Targeting Receptor Tyrosine Kinase Signalling: Avenues in the Management of Cutaneous Squamous Cell Carcinoma

[iScience] Scientists discuss the relevance of receptor tyrosine kinases (RTK) signaling in the progression of cutaneous squamous cell carcinoma, and observations from clinical trials that used RTK inhibitors against cutaneous squamous cell carcinoma

Cachexia: A Systemic Consequence of Progressive, Unresolved Disease

[Cell] The authors review drivers, mechanisms, organismal predispositions, evidence for multi-organ interaction, model systems, clinical research, trials, and care provision from early onset to late cachexia.

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