Review

[Angiogenesis] Scientists provide an overview of the chip designs and culturing strategies employed for vascularized organoid-on-a-chip, as well as the applicable optical imaging and tissue optical clearing methods.

[Nature Reviews Drug Discovery] Investigators provide an outlook into next-generation bispecific antibodies (bsAbs) in earlier stages of development, including trispecifics, bsAb prodrugs, bsAbs that induce degradation of tumour targets and bsAbs acting as cytokine mimetics.

[Pigment Cell & Melanoma Research] The authors provide an updated review on melanin metabolism and discuss the many aspects of melanin synthesis that intersect with metabolic pathways known to impact melanoma phenotypes and behavior.

[International Journal Of Cancer] The authors summarize the interaction mechanisms and biological significance of N6-methyladenosine (m6A) modifications and non-coding RNAs in breast cancer, focusing on the clinical application value of m6A modification in breast cancer diagnosis and prognosis.

[HIV Medicine] The authors provide insight into the impact of HIV and mpox co-infection on clinical outcomes. These findings highlight the significance of early diagnosis, prompt treatment initiation, and effective management strategies for people living with HIV and mpox.

[Small] Scientists provide overview of the categories of nanoplatform-based non-viral gene vectors, the limitations on their development, and their applications in cancer therapy.