Review

[Endocrine Reviews] The authors review pivotal hormones controlling human skin aging focusing on IGF-1, a key fibroblast-derived orchestrator of skin aging, of GH, estrogens, retinoids, and melatonin.

[Trends in Molecular Medicine] Investigators summarize advancements in asparagine endopeptidase inhibitors, their mechanisms of action, therapeutic applications in neurodegenerative diseases, and the challenges in translating these findings into clinical practice.

[Developmental Cell] The authors discuss the basic principles underlying organoids generated from PSCs as well as those derived from tissue stem cells.

[Nature Reviews Urology] Chemotherapies such as docetaxel and cabazitaxel, along with emerging targeted therapies and radiopharmaceuticals, are associated with varied cardiovascular risks, necessitating personalized patient assessment.

[Molecular Cancer] The authors highlight the critical role of cancer stem cells and their niche in driving immunotherapy resistance, emphasizing the need for integrative approaches to overcome these challenges.

[Trends In Immunology] The authors propose that differences in the metabolic and stress responses between T cell subsets upon thermal stress contribute to determining immune cell makeup and fate during inflammation.