Review

[Molecules and Cells] Scientists highlight the role of transcription factors in neuroendocrine prostate cancer development and explore their potential as therapeutic targets.

[Progress In Lipid Research] The authors provide an overview of metabolomic changes in TNBC with emphasis on lipid alterations, and describe the key mass spectrometry analytical techniques, providing the necessary background for examining the role of lipids in TNBC development.

[Coordination Chemistry Reviews] The authors elucidate the niche characteristics of CSCs and the use of biomedical engineering to target CSC characteristics, including surface markers, the microenvironment associated with CSCs, related signaling pathways, and differentiation therapy aimed at improving tumor treatment.

[Nature Reviews Molecular Cell Biology] Investigators highlight recent structural and functional insights into the activation of insulin– insulin-like growth factor (IGF) receptors, and summarize new agonists and antagonists developed for intervening in the activation of insulin–IGF receptor signaling.

[Apoptosis] The authors summarize the cell death subroutines in the erythroid precursors in comparison to mature erythrocytes to highlight the consequences of organelle clearance and associated loss of multiple components of the cell death machinery upon erythrocyte maturation.

[Cold Spring Harbor Perspectives in Medicine] Scientists review key features of several genetic predisposition syndromes (GPS) associated with increased risks for hematologic malignancy while also outlining the diagnostic workup to identify GPSs and treatment considerations for affected patients.