vascular endothelial cells

[Biochemical Pharmacology] Investigators demonstrated that the C1q-like globular domain of C1q/tumor necrosis factor-related protein (CTRP)3, CTRP5, and CTRP9 exerted a vasorelaxant effect on the microvasculature, of which gCTRP3 was the most powerful one.

[Autoimmunity] Cerulean and LPS was used to establish a rat model and an in vitro model of severe acute pancreatitis. qRT-PCR, western blot and IHC were determined to analyse the expression of mRNA and proteins. IL-1β, TNF-α and IL-6 levels were measured applying ELISA.

[Journal of Animal Science and Biotechnology] Researchers investigated the potential of cysteamine as an antioxidant protectant for regulating the reproductive performance, redox status, and placental angiogenesis of sows.

[Scientific Reports] Human umbilical vascular endothelial cells were cultured with or without COL-4A1 and TNF-α. Cell Counting Kit-8, wound-healing, Transwell and tube formation assays were used to evaluate cell proliferation, migration and angiopoiesis.

[AAPS Journal] Scientists summarize the current understanding of exosome biogenesis and uptake, and discuss atherogenic and atheroprotective functions of exosomes secreted from these cell types.

[Vascular Pharmacology] The authors summarize the biogenesis, characteristics and functions of circRNAs with a focus on their roles in the pathogenesis of atherosclerosis.