The COL-4A1 Polypeptide Destroy Endothelial Cells through the TGF-β/PI3K/AKT Pathway

Human umbilical vascular endothelial cells were cultured with or without COL-4A1 and TNF-α. Cell Counting Kit-8, wound-healing, Transwell and tube formation assays were used to evaluate cell proliferation, migration and angiopoiesis.