[International Journal of Molecular Medicine] The authors investigated the antitumor effects of Ailanthone on HCT116 and SW620 colon cancer cells, and to analyze the underlying molecular mechanisms.
[Journal of Experimental & Clinical Cancer Research] The authors elucidated the multifaceted role of adiponectin in tumor fatty acid metabolic reprogramming and provided evidence for the connection between its metabolic actions and suppression of breast cancer.
[Biochemical Genetics] The authors investigated the role of circular RNA F-box and WD repeat domain containing 8 (circFBXW8) in NSCLC progression and the underlying mechanism.
[Cell Death & Disease] This research was designed to explore the mechanism underlying the OLR1/c-MYC/SULT2B1 axis in the regulation of glycolytic metabolism, to affect colon cancer cell proliferation and chemoresistance.
[Experimental Dermatology] In the skin, UV-irradiation increases expression of matrix metalloproteinases (MMPs) that causes dysregulation of extracellular matrix homeostasis in dermis, leading to acceleration of skin aging. Researchers reported the role of transglutaminase 2 in mediating the UVB-induced expression of MMP-1.
[Prostate] The authors investigated a combination therapy of novel androgen receptor (AR) antagonists and statin, simvastatin, for CRPC and found that a combination of novel AR antagonists and simvastatin could potentially affect CRPC growth through both androgen-dependent and androgen-independent mechanisms.